Laboratory of Comparative Cognition

Preprints

• Frostig, H., Monasterio, A., Shvedov, N.R., Xia, H., Mishra, U., Britton, B., Giblin, J.T., Mertz, J., and Scott, B.B. (2025). Three-photon population imaging of subcortical brain regions. bioRxiv. https://doi.org/10.1101/2025.03.21.644611

• Monasterio, A., Lienkaemper, C., Coello, S., Ocker, G. K., Ramirez, S., & Scott, B. B. (2024). CA1 engram cell dynamics before and after learning. bioRxiv. https://doi.org/10.1101/2024.04.16.589790

Publications

2025

• Chakravarty, S., Delgado-Sallent, C., Kane, G. A., Xia, H., Do, Q., Senne, R. A., & Scott, B.B. (2025). A cross-species framework for investigating perceptual evidence accumulation. eLife.14:RP105116. https://doi.org/10.7554/eLife.105116.1

• Affan, R.O., Bright, I.M., Pemberton, L., Cruzado, N.A., Scott, B.B. and Howard M. O. (2024) Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning. Journal of Neurophysiology. https://doi.org/10.1152/jn.00234.2024

2024

• Kane, G.A., Senne, R.A. and Scott, B.B. (2024) Rat movements reflect internal decision dynamics in an evidence accumulation task. Journal of Neurophysiology. https://doi.org/10.1152/jn.00181.2024 PDF

• Affan, R.O., and Scott B.B. (2024) High-resolution tracking of internal model formation using automated live-in training. Conference on Cognitive Computational Neuroscience. PDF

• Rich, P.D., Thiberge Y.S., Scott B.B., Guo C., Tervo D.G.R., Brody C.D., Karpova, A.Y., Daw, N. and Tank D.W. (2024) Magnetic voluntary head-fixation in transgenic rats enables lifetime imaging of hippocampal neurons. Nature Communications. https://doi.org/10.1038/s41467-024-48505-9

• Shvedov, N.R., Analoui, S., Dafalias, T., Bedell, B.L., Gardner, T.J., and Scott, B.B. (2024) In vivo imaging in transgenic songbirds reveals superdiffusive neuron migration in the adult brain. Cell Reports. https://doi.org/10.1101/2023.07.14.548876

  • Previewed in: Migratory neurons in adult songbirds spread their wings. Sorrells, S.F. Cell Reports. https://doi.org/10.1016/j.celrep.2024.113848

  • Spotlight in: Window into the songbird brain reveals superdiffusive migration of adult-born neurons. Pytte, C.L. TINS. https://doi.org/10.1016/j.tins.2024.04.001

2023

• Do, Q., Hasselmo M.E., Scott, B.B. (2023) Generalization in an Evidence Accumulation Task. Conference on Cognitive Computational Neuroscience. https://doi.org/10.32470/CCN.2023.1410-0

• Do, Q., Li, Y., Kane, G.A., McGuire, J.T. and Scott, B.B. (2023) Assessing evidence accumulation and rule learning in humans with an online game. Journal of Neurophysiology. https://doi.org/10.1152/jn.00124.2022

2022

• Kim, S.J., Slocum A.H. and Scott B.B. (2022) A miniature kinematic coupling device for head-restraint in mice. Journal of Neuroscience Methods. https://doi.org/10.1016/j.jneumeth.2022.109549

• Charles A.S., Cermak N., Affan R., Scott B.B. , Schiller J. and Mishne G. (2022) GraFT: Graph filtered temporal dictionary learning for functional neural imaging. IEEE Transactions on Image Processing. https://doi.org/10.1109/TIP.2022.3171414

2018

• Scott B.B., Thiberge Y.S., Guo C., Tervo D.G.R., Brody C.D., Karpova, A.Y. and Tank D.W. (2018) Imaging cortical dynamics in GCaMP transgenic rats with a head-mounted widefield macroscope. Neuron. https://doi.org/10.1016/j.neuron.2018.09.050 - Video Abstract

Before 2018

• Scott B.B., Constantinople C.M., Akrami A., Hanks T., Brody C.D. and Tank D.W. (2017) Fronto-parietal cortical circuits encode accumulated evidence with a diversity of timescales. Neuron. https://doi.org/10.1016/j.neuron.2017.06.013 - Video Abstract

• Scott B.B., Constantinople C.M., Erlich J.C., Tank D.W. and Brody C.D. (2015) Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats. eLife. https://doi.org/10.7554/eLife.11308

• Scott B.B., Brody C.D. and Tank D.W. (2013) Cellular resolution functional imaging in behaving rats using voluntary head restraint. Neuron. https://doi.org/10.1016/j.neuron.2013.08.002

• Scott B.B., Gardner T., Ji N., Fee M.S. and Lois C. (2012) Wandering neuronal migration in the postnatal vertebrate forebrain. Journal of Neuroscience. https://doi.org/10.1523/JNEUROSCI.2145-11.2012 - Video

• Agate R.J., Scott B.B., Haripal B., Lois C., and Nottebohm F. (2009) Transgenic songbirds offer an opportunity to develop a genetic model for vocal learning. Proceedings of the National Academy of Sciences. USA. https://doi.org/10.1073/pnas.0909139106

• Scott B.B. and Lois C. (2007) Developmental origin and identity of song system neurons born during vocal learning in songbirds. Journal of Comparative Neurology. https://doi.org/10.1002/cne.21296 (PDF)

• Scott B.B. and Lois C. (2006) Generation of transgenic birds with replication-decient lentiviruses. Nature Protocols. https://doi.org/10.1038/nprot.2006.187

• Scott B.B. and Lois, C. (2005) Generation of tissue-specific transgenic birds. Proceedings of the National Academy of Sciences. USA. https://doi.org/10.1073/pnas.0508437102

Reviews, Opinions, Perspectives

• Scott, B.B. (2024) Computational and systems neuroscience needs development. Transmitter. https://doi.org/10.53053/TRPW5375

• Kim, S.J., Affan, R. O., Frostig, H., Scott, B.B., and Alexander, A.S. (2023) Advances in cellular resolution microscopy for brain imaging in rats. Neurophotonics. https://doi.org/10.1117/1.NPh.10.4.044304

• Affan, R.O and Scott B.B. (2022) Everything, everywhere, all at once: Functional specialization and distributed coding in the cerebral cortex. Neuron. https://doi.org/10.1016/j.neuron.2022.07.006

• Scott, B.B., Velho, T.A., Sim, S. and Lois, C., (2010) Applications of avian transgenesis. ILAR journal, 51(4), pp.353-361. https://doi.org/10.1093/ilar.51.4.353

• Scott, B.B. and Sanjana, N.E., (2009) The Wanderlust of Newborn Neocortical Interneurons. Journal of Neuroscience, 29(22), pp.7114-7115. https://doi.org/10.1523/JNEUROSCI.1624-09.2009

• Chen, J., Chen, S.C.Y., Stern, P., Scott, B.B. and Lois, C. (2008) Genetic strategy to prevent influenza virus infections in animals. The Journal of infectious diseases, 197(Supplement_1), pp.S25-S28. https://doi.org/10.1086/524987

• Scott, B.B. and Lois, C. (2006) Production of transgenic birds using lentiviral vectors. In Mammalian and Avian Transgenesis—New Approaches (pp. 221-230). Berlin, Heidelberg: Springer Berlin Heidelberg.